Interleukin-1 beta
Inflammation markersA key inflammatory mediator that triggers bone resorption in periodontal disease.
This is information about your result, not a diagnosis. Your provider can tell you what it means for you.
What is Interleukin-1 beta?
Interleukin-1 beta (IL-1β) is one of the most potent pro-inflammatory cytokines. In periodontitis, it is produced by immune cells in response to bacterial products and directly stimulates osteoclasts, the cells responsible for bone breakdown.
Why it matters
IL-1β plays a central part in the bone loss seen in gum disease. A high level is associated with inflammation that may be affecting the bone, not just the gums. Some people naturally produce more IL-1β than others.
What a high result can mean
A high level is associated with bone loss around the teeth, especially alongside high bacteria levels. It is worth discussing with your dentist soon.
What usually happens next
Your dentist will usually focus on reducing the bacteria first, and may talk with you about treatments that calm the inflammation.
Related markers
This page explains what the test measures. It is not a diagnosis, and it cannot tell you what your result means for you. Your provider can.